Course introduction
With recent advances in molecular biology and a growing biomass availability for use as industrial feedstock, the biobased economy is getting a wider range of inputs. Scaling up the bio(techno)logy innovations and implementation in large-scale factories or biorefineries clearly is a present bottleneck: industries are struggling to get the bio-opportunities to the market, as experienced industrial bioprocess designers and operational experts are not readily available to meet the growing needs.
Teachers from universities and companies have joint forces and will present a program that centres around industrial fermentation processes, and is flanked by overviews on upstream and downstream processing. The focus of the course is on design of innovative microbial fermentations, for bio-products such as amino acids and monomers for bio-plastics, complemented with examples of marine and mammalian processes, for micro-algae products and bio-pharmaceuticals. A substantial part (ca. 40% of the time) will be dedicated to a case study, executed in teams of 4-6 participants, on the design of a bioprocess for the production of a chemical (1,4-butanediol). Basic theory on thermodynamic, microbial stoichiometry and kinetics, transport phenomena and scale up/down will be extensively applied and integrated. The team with the best design performance wins the Genomatica Bioprocess Design prize. Several guest lecturers from leading universities and industries in the bioprocess field, provide latest insights in technology innovations, non-conventional feedstocks and new bioproduct categories, complemented with views from the industrial practice.
The Advanced Course Bioprocess Design is cooperatively organised by
Biotech Delft and VLAG Graduate School.
16 - 20 September 2024
Biotech Campus Delft (DSM)
Alexander Fleminglaan 1
2613 AX Delft, the Netherlands
Advanced Course Bioprocess Design
Programme
- Rates, thermodynamics and metabolism of micro organisms
- Transport processes in bioreactors
- Fermentation processes and their scale up features
- Examples of successful bioprocesses, downstream processing, novel feedstocks and economic aspects of bioprocessing.
Study load
The course (including preparatory materials) is valued 48 hours of work.
Advanced Course Bioprocess Design
Who should attend?
The course is primarily aimed at academic and industrial specialists (MSc, PhD or equivalent experience) that seek for refreshing and broadening their knowhow and practical insight in Bioprocess Design, to assist in progress towards the bio-based economy. A background in e.g. biochemical engineering, microbiology or biochemistry and a basic working knowledge of the other disciplines is required.
Advanced Course Bioprocess Design
Fee
*To be eligible for the reduced early bird fee you need to register before 8 July 2024. If this date is exceeded, the regular fee applies.
**A limited number of fellowships is available for PhD students and SME’s (small/medium enterprise). Fellowships will be available on a first-come-first-serve basis. To apply as to one of these fellowships, please include a copy either of your registration as a PhD student from your university or a proof of the SME-status of the company you work at.
The fee includes course materials, lunches and the buffets and the course dinners as indicated on the program. The fee does not cover other meals or lodging.
The course fee
Early bird*
€ 2.500,-
Regular fee
€ 2.750,-
Small and medium-sized enterprises (SME/Startups/scaleups)**
€ 1.750,-
Small and medium-sized enterprises (SME/Startups/scaleups) of Biotech Campus Delft**
€ 1.250,-
PhD Students**
€ 1.250,-
Advanced Course Bioprocess Design
Course board members
Prof.dr.ir. Henk Noorman
Board member
Prof.dr.ir. (Emeritus) Sef Heijnen
Board member
Prof. Ruud Weusthuis
Board memberAdvanced Course Bioprocess Design
Downloads
Advanced Course Bioprocess Design
Register
After registration you will receive a confirmation e-mail from us and another email with an invoice. We look forward to welcoming you in our course in Delft!Note
A limited number of fellowships is available for PhD students (reduced fee). Deadline for registration is 26 August 2024.Advanced Course Bioprocess Design
Register
Advanced Course Bioprocess Design
Testimonials
Max Völker
Mushlabs GmbH, Germany As an inorganic chemist working in a biotech startup, I needed a way to get access to experience in industrial process design. Learning from literature is great but a bit one-directional. Talking to experts with decades of combined experience and being able to ask silly questions and having them answered is priceless. Read moreMax Völker
Mushlabs GmbH, Germany As an inorganic chemist working in a biotech startup, I needed a way to get access to experience in industrial process design. Learning from literature is great but a bit one-directional. Talking to experts with decades of combined experience and being able to ask silly questions and having them answered is priceless. The combination of theoretical presentations followed by real life examples where these principals were applied and helped to improve these processes was amazing to see. Having a heterogeneous group of participants with all kinds of backgrounds was a delight and sparked some interesting conversations. The knowledge I took home directly helped me to improve our process and I was able to implement certain concepts for better efficiency evaluations that were taught in the course. 2022
Omnia AbdelKarim
PhD Wageningen University, the Netherlands & Assistant lecturer Tanta University, Egypt The advanced bioprocess design course is very perceptive with many different topics and offers a great opportunity to amplify the ability to combine theoretical calculations with the real applications of biological processes in the industry. It was a strong one-week course filled with speakers from different areas Read moreOmnia AbdelKarim
PhD Wageningen University, the Netherlands & Assistant lecturer Tanta University, Egypt The advanced bioprocess design course is very perceptive with many different topics and offers a great opportunity to amplify the ability to combine theoretical calculations with the real applications of biological processes in the industry. It was a strong one-week course filled with speakers from different areas It was a strong one-week course filled with speakers from different areas like industries and academia, providing several insightful topics where we learned the principles behind process design and scaling up biotechnology innovations and implementation on large or small scales. Also, it has a good balance between the lectures and the practical exercises, especially the case study, to know how we can design a feasible process and what the bottlenecks and how we can improve our process by implementing the knowledge learned. In addition to that, the competitive case studies and working in groups not focusing only on the scientific area but also we learned how to share ideas within the group and how to work as a team to achieve success for the whole team, and I think that is the most important part in the industry. Moreover, it is a good opportunity to meet experts from different fields and to ask all the lectures detailed questions. The course was very organized, and they covered every biotechnological aspect from theoretical to practical and connected this with real industry in the BPF tour we made. As I am a (micro)biologist working on lipid production from microalgae, and I need to learn about the reactor design, the bottlenecks, and the steps needed for the scale-up process of lipid production and this course helped to understand how to set my own process design from the product’s stoichiometry to the scale-up stage to guarantee the process victory and undoubtedly the course met my all expectations. So, I strongly recommend this course to a (micro)biologist who wants to learn more about biotechnology and needs to gain advanced knowledge of technical aspects of bioprocess design. 2022
Helin Alagoz
EV Biotech, Fermentation Scientist I am a bioengineer by training but passionate about fermentation and bioprocess design. I took the Advance Bioprocess Design course to deepen my knowledge in the field and learn more about scaling up methodology and applying it in real life. The course had very insightful topics where we learned the principles behind process design Read moreHelin Alagoz
EV Biotech, Fermentation Scientist I am a bioengineer by training but passionate about fermentation and bioprocess design. I took the Advance Bioprocess Design course to deepen my knowledge in the field and learn more about scaling up methodology and applying it in real life. The course had very insightful topics where we learned the principles behind process design I am a bioengineer by training but passionate about fermentation and bioprocess design. I took the Advance Bioprocess Design course to deepen my knowledge in the field and learn more about scaling up methodology and applying it in real life. The course had very insightful topics where we learned the principles behind process design from full-scale and was supported by a case study for the production of 1,4-butanediol and butadiene, where we applied our new learnings in bioreactor design in the last 3 days. The course has a tight schedule and is intensive, so I recommend brushing up on thermodynamics and biokinetics for those who want to take it and have not used this knowledge recently. The course was enlightening and very well presented by expert lecturers from academia and industry, we also had several social settings where we interacted with professionals with the same interests from a variety of disciplines. I enjoyed the small group dynamics with the lecturers and participants and I would highly recommend this course to anyone wishing to learn more about bioprocess design and challenge themselves. Overall, I had a great experience thanks to the organizers, lecturers, and my team during the course. 2021
Peter Ehlert Jensen
Junior Fermentation Engineer at The Novo Nordisk Foundation Center for Biosustainability As a chemical engineering graduate working in the field on fermentation science with emphasis on scale up/down methodology this course was enlightening. The intense course schedule coupled with challenging and interesting case studies made the whole experience engaging and fun. Read morePeter Ehlert Jensen
Junior Fermentation Engineer at The Novo Nordisk Foundation Center for Biosustainability As a chemical engineering graduate working in the field on fermentation science with emphasis on scale up/down methodology this course was enlightening. The intense course schedule coupled with challenging and interesting case studies made the whole experience engaging and fun. The teachers held a high standard of expertise in their respective fields and were able to elaborate complex material in a simplistic manner. The guest lectures provided interesting topics, which could relate the course material to real-life scenarios in the current age of bioprocess design. Last and not least, the social activities were delightful and provided with a great opportunity to connect with likeminded individuals to socialize and in general having a good time. I would highly recommend the course to any who wants to challenge their own knowledge in Bioprocess Design and be part of the industrial biotechnology journey. 2021
Marcel Girard
Junior Fermentation Engineer at The Novo Nordisk Foundation Center for Biosustainability Former as well as current colleagues and supervisors recommended this course to me, which is why I had quite high expectations of it. These expectations were met completely. As an MSc. In Biotechnology, the course was very valuable, giving insights more into Chemical Engineering and the production of mostly small molecules. Read moreMarcel Girard
Junior Fermentation Engineer at The Novo Nordisk Foundation Center for Biosustainability Former as well as current colleagues and supervisors recommended this course to me, which is why I had quite high expectations of it. These expectations were met completely. As an MSc. In Biotechnology, the course was very valuable, giving insights more into Chemical Engineering and the production of mostly small molecules. Former as well as current colleagues and supervisors recommended this course to me, which is why I had quite high expectations of it. These expectations were met completely. As an MSc. In Biotechnology, the course was very valuable, giving insights more into Chemical Engineering and the production of mostly small molecules. The course had a good balance of lectures and practical exercises with a focus on planning a techno-economically viable bioprocess. The lectures gave a good summary of the state of the art in bioprocess design as well as current challenges in the field. The one-course week was quite intense, but there was plenty of time to socialize and get to know organizers and participants alike. In summary, I can highly recommend this course especially for people that want to extend their knowledge in Bioprocess Design for bulk chemicals. 2021
Sivaramakrishnan Chandrasekaran
Ph.D. Candidate in Sustainable process design, Delft University of Technology For a person with background in Chemical Engineering and passion for biotechnology, this course was very insightful with diverse topics and an interesting case study to understand about bioprocess design. The one week intensive course was filled with speakers from industries and academia Read moreSivaramakrishnan Chandrasekaran
Ph.D. Candidate in Sustainable process design, Delft University of Technology For a person with background in Chemical Engineering and passion for biotechnology, this course was very insightful with diverse topics and an interesting case study to understand about bioprocess design. The one week intensive course was filled with speakers from industries and academia providing apt environment to learn about the sector as a whole. The course is set at medium/advanced level with special focus on bioreactor design. The learning curve for this advanced course depends on professional background of an individual but all support was provided to achieve the same. The key highlight of the course is the opportunity to develop a process design in a case study where we could implement the knowledge learned. I highly recommend this course to people whose current work is related to experimental or conceptual design of biochemical/biotechnological process engineering. Finally, the course takes place in the modern building of DSM located in the small and beautiful city of Delft providing an energetic environment to get to know fellow candidates and speakers. 2021
Frederik Michale
EngD, TU Delft I joined the AC Bioprocess Design because I wanted to learn how to solve problems and design solutions in USP simply and pragmatically. Read moreFrederik Michale
EngD, TU Delft I joined the AC Bioprocess Design because I wanted to learn how to solve problems and design solutions in USP simply and pragmatically. The scheduling of the topics covered in the course was in good order, starting from thermodynamics to obtain the process reaction, gas-liquid mass transfer, reactor design, and ending with the design of experiments for scale-down testing. Besides learning, there was enough time to apply all the knowledge in a group case study which was in my opinion the best part of the course. I was happy to have the opportunity to join this course and I believe people who want to bring a more abstract and scientific approach to bioreactor design to their companies will benefit from taking this course. 2023
Elizabeth Geddes
Lead Process Engineer, TransitionHERO I work for TransitionHERO, as a specialist in innovation and scaling-up green technologies. I was motivated to take this course after seeing a shift in industry more and more towards using fermentation as a way of valorising waste streams to make new chemicals or food sources. Read more